권호 일람







년도별 일람

Total 48건 1 페이지
48 2015

상악 전치부에 임플란트 식립 후 발생한 비구개관낭 : 증례 보고

저자 임헌준


The nasopalatine duct cyst is the developmental non-odontogenic cyst caused by epithelium remnants of fetal nasopalatine duct. The trauma of incisive canal associated dental implant placement in the anterior maxilla can cause the nasopalatine duct cyst. It is difficult to identify the nasopalatine duct cyst or the location of the incisive canal, only using periapical radiograph or panorama radiograph. So it is necessary to take computed tomography scan for an analysis on the relation between the implant and the incisive canal. This case report present the patient had the nasopalatine duct cyst following the placement of dental implant in the anterior maxilla, and was undergone implant removal and cyst enucleation with bone graft.

47 2015

하악골의 유피낭종 : 증례 보고

저자 박정원, 김륜가, 노상화, 정태영, 박상준


We report a rare case of intraosseous epidermoid cyst in mandibular body. A non symptomatic patient without trauma history had a cystic lesion on mandible close to the third molar. The lesion was enucleated while extracting of left lower third molar. The microscopic findings were consistent with an epidermoid cyst.

46 2015

경부에서 발생한 편평상피암종과 신경섬유종의 충돌종양- 증례보고 및 문헌고찰 -

저자 임재형, 나리수, 김지선, 조혜중, 김서진, 최홍란, 김옥준


It is very rare case to observe the one lesions within two types of tumors at the same time. These case classified into two types according to histopathological characteristics. One is composite tumor, and the other is collision tumor. Composite tumor is a lesion showing the combined histopathological characteristics of two or more previously recognized tumor and/or cysts of different categories. Two constituent parts are mixed with each other, and histological transition is often observed. On the other hand, collision tumor is a lesion showing the independent histopathological characteristics of two or more previously recognized tumor and/or cysts of different categories. Two constituent parts are separated each other by connective tissue, and histological transition is not observed. Their origin is still unclear. In this study, a collision tumor was reported. 77-year old woman was referred to CNUH with a neck mass in right submandibular area. Incisional biopsy was carried out, and the patient was diagnosed as collision tumor of squamous cell carcinoma and neurofibroma. After reviewing studies reporting collision tumor from head and neck area, formation of a collision tumor was most frequent from a cervical area and average age is 59.6. A collision tumor commonly lead to misdiagnosis, and the prognosis is not always transparent. The variety symptom of collision tumor has to be kept in mind in the diagnosis and treatment of the lesions in head and neck area.

45 2015

건전 상아질과 우식 상아질에서 matrix metalloproteinase-13의 발현 양상 분석

저자 이태연


Matrix metalloproteinases (MMPs) are proteolytic enzymes involved in degradation of the extracellular matrix.In a previous study, MMP-13 was found to be expressed in pulp implying its involvement in the pathogenesis of dental caries. Two extracted teeth were used. A sound tooth and a tooth with wide range of dental caries were used. Two sections were obtained each from isolated crown and root. Immunofluorescence of the FITC of the MMP-13 in coronal and radicular dentin was analyzed by confocal microscopy. Immunofluorescence signals that were indicative of MMP-13 were observed in coronal dentin of sound teeth and in carious teeth with a wide range of caries. Marked immunofluorescent reaction was observed in the border line of caries infected and affected coronal dentin. MMP-13 expression was not detected in the root dentin. The expressions of MMP-13 in carious dentin imply the roles of MMP-13 in caries progression.

44 2015

상악에 발생한 모균증 증례보고

저자 윤성원, 김철만, 권대근, 팽준영, 김진욱, 신홍인, 최소영


Mucormycosis generally presents as an acute infection manifesting in rhinocerebral, pulmonary, gastrointestinal, cutaneous, or disseminated forms. Fungal invasion to the arteries can reduce blood supply by thrombi formation inside the blood vessels, leading to necrosis. Fungal infection usually initiates in the upper turbinate, paranasal sinus, or less commonly in the palate or pharynx. Here we report an unusual case of mucormycosis in the maxilla of a 75-year-old man and present a review of the literature.

43 2015

체루비즘 : 증례보고

저자 임헌준


Cherubism is a rare familial multilocular cystic disease of the jaws. Cherubism mostly has an autosomal dominant inheritance. This disease mainly occurs in children, has a tendency toward spontaneous remisson after puberty. Clinically, it shows bilateral bone enlargement of the jaws and multilocular cystic lesion on radiograph. Histologically, the lesion shows fibrovascular stroma and osteoblast like multinucleated giant cell. These features are similar to other bone disease such as central giant cell granuloma. So it needs differential diagnosis by clinical, radiological and histophathologic examinations. We report with review of literatures the fifteen years old male patient who had diagnosed as cherubism by clinicoradiological and histopathologic examination results.

42 2015

구개부에 발생한 다형선종 : 증례 보고 및 문헌 고찰

저자 김준규, 윤현중, 이재일, 이상화


Pleomorphic adenoma is the most common benign tumor of the salivary glands. About 90% of these tumors occur in the parotid gland and 10% of them occur in the minor salivary glands. The most common sites for pleomorphic adenoma of the minor salivary glands are the palate, followed by the lips and the cheeks. Pleomorphic adenoma of the palate presents clinically as a painless, slow-growing mass found on posterior lateral aspect. In this case report, we report a case of pleomorphic adenoma of the palate in a 36-year old male patient whose initial diagnosis was vascular mass such as hemangioma or lymphangiohemangioma by preoperative CT and MRI.

41 2015

사람 침단백질 복합체의 면역침전 고수행 액체크로마토그라피 분석

저자 김연숙, 이석근


In order to know the characteristic roles of salivary protein complex (SPC) the gel-filtration chromatography was performed using the unstimulated and the stimulated whole saliva separately. The first and second dominant SPC peaks were fractionated and analyzed by immunoprecipitation HPLC (IP-HPLC) using antibodies against the essential salivary proteins including α-amylase, mucin-1, proline rich proteins (PRPs), histatin, cystatin, LL-37, lysozyme, lactoferrin, -defensin-1, -2, -3, IgA, transglutaminase 4 (TGase 4), mucocidin, α1-antitrypsin, cathepsin G. In the gel-filtration chromatography the stimulated whole saliva showed much reduced amount of SPCs than the unstimulated whole saliva, but the proportional patterns of both whole saliva were almost similar each other. Through IP-HPLC analysis both of the first and second dominant SPCs were variably positive for the essential salivary proteins, however, α-amylase, mucin-1, PRPs, lysozyme, and cathepsin G were predominant in the first dominant SPC, while cystatin, lactoferrin, β-defensin-1, -2, -3, IgA, mucocidin, TGase 4, and α1-antitrypsin were predominant in the second dominant SPC. And more, the α1-antitrypsin and cathepsin G which were mostly derived from gingival crevicular fluid were also consistently found in the SPCs. These data may suggest that the first dominant SPC, rich in α-amylase, mucin-1, PRPs, lysozyme, and cathepsin G, may play a role in food digestion, protein degradation, and mucosa lubrication, while the second dominant SPC, rich in cystatin, lactoferrin, β-defensin-1, -2, -3, mucocidin, IgA, TGase 4, and α1-antitrypsin, may play a role in the mucosa protection and antimicrobial defense.

40 2015

Air-flow equipment를 사용한 치주치료 이후 발생한 종격동 기종과 피하기종 :-증례보고-

저자 이정헌, 김강혁, 김준규, 박재억, 김창현


Subcutaneous emphysema is a rare but serious side effect of dental and oral surgery procedures. The condition is characterized by air being forced underneath the tissue, leading to swelling, crepitus on palpation, and with potential to spread along the fascial planes to the periorbital, mediastinal, pericardial, and/or thoracic spaces. A wide range of causes have been documented for the origin of subcutaneous emphysema during dental treatment including: crown preparations, other operative procedures, endodontic therapy, extractions, as well as oral surgery procedures. The patient was a 58-year-old woman who presented to the Seoul Saint mary’s hospital emergency department with a chief complaint of facial edema, dyspnea and chest discomfort after periodontal treatment using an air-flow equipment in local dental clinic. During treatment in the emergency department, oxygen therapy and intravenous injection of steroid and anti-histamine was done. it was noted that the patient had pain and swelling on left lower molar region, pus discharging on same site. Severe edema was observed on periorbital region to neck with heatness. An audible crepitus sound was heard during palpation on facial area. Neck CT scan and antibiotic therapy was done, as symptom suggesting dental abscess is observed. 3 hours after injection of antibiotics, the patient’s symptom was relieved, but she felt chest discomfort continuously. CT scan with constrast depicted confluent and extensive soft tissue emphysematous changes involving face and deep neck spaces and pneumomediastinum. The patient was refered to thoracic surgery department, oxygen therapy was decided continuously. After 10 hours, patient’s chief complaint was resolved, and discharged. After 1 week, all symptom was disappear and follow-up neck CT scan finding was disappearance of edema and pnuemomediastinum. We report a case of cervical subcutaneous emphysema and pneumomediastinum occurring after periodontal treatment using an air-flow equipment and case on the diagnosis and treatment of subcutaneous emphysema and pneumomediastinum, along with a review of the literature.

39 2015

혀에 발생한 유아섬유종증 증례 보고와 그 분류에 대한 고찰

저자 강경림, 신의정, 윤혜정, 이재일, 홍삼표, 홍성두


Fibromatoses are benign fibroblastic proliferation, which forms infiltrating tumor-like mass. Their histologic features cannot reflect the biologic behavior; local recurrence and aggressive infiltration to the adjacent tissue make fibromatoses intermediate tumor, between benign and malignant. Infantile fibromatosis consists of desmoid-type tumor and lipofibromatosis, and mainly affects children under age of 10. While desmoid-type tumor is characterized by elongated mature fibroblastic proliferation, the fibroblasts in lipofibromatosis look more primitive and accompany adipocytes. Here, we report a case of infantile fibromatosis of 4 month old boy involving the tongue.

38 2015

하악 제 3 대구치와 연관된 질환에 영향을 미치는 요인

저자 오지민, 윤숙자


"The aim of this study was to analyze factors indicating preventive removal of mandibular third molars by determining associated symptoms, pathologies, eruption state, position and angulation types of mandibular third molars.A retrospective study was made of 436 patients(200 females, 236 males), aged between 12 and 81 years (mean: 29.93 years) undergoing panoramic radiographic examinations. Total 700 mandibular third molars were analyzed. They were divided by age, sex, position and angulation of mandibular third molars, bony coverage, and associated pathologies- caries, pericoronitis, periodontitis, cyst, root resorption of adjacent teeth. Among 409 pathologies associated with mandibular third molars, pericoronitis accounted for 34.2%(140 cases), which was the most common lesion, caries in the second and third molars for 28.9%, caries in the second molars for 11%(45 cases). Periodontitis showed in 7%(29 cases). In 4 cases, root resorption of adjecent tooth showed. The position which showed predominant pathologic lesion according to the Pell and Gregory classification was ‡UA(86.5%), followed by ‡UB(71.6%). Mandibular third molars without bony coverage(64.8%) showed pathologies frequently.The removal of mandibular third molars must be determined by the perceived risk if the teeth are not removed. The position and inclination of the third molars, bony coverage, age and sex of patients can be the important evidence in the decision making process."

37 2015

구강편평상피세포암종 세포주에서 YAP의 발현

저자 김지연, 홍지수, 이재일, 홍성두, 이상진


"Hippo signaling is one of the signal transduction pathways revealed in Drosophila and mammalian. This signaling is known to control proliferation and growth of normal cells or cancer cells, in which many signaling proteins form a network. In this network, tumor suppressor kinases include MST and LATS while YAP and TAZ exist as oncoproteins. Combined with transcription factor, YAP the oncoprotien starts to secrete growth factors such as CTGF, FGF, and Cry61 regulating the growth of cells or the organ sizes. The YAP is also associated with the development of early embryo and the regeneration of the skin wound as well as abnormal growth of cancers in case of over-expression. Although many previous studies have found various tumors with YAP over-expressed, the expression of YAP is not yet clearly identified in oral cancer.The aim of this study was to check the expression level of YAP in oral squamous cell carcinoma. So we performed PCR and Western blot to check YAP expression in mRNA and protein level respectively. In result, all of the 13 cell lines examined has presented the expression of YAP, and especially in HSC2 and KOSCC11 cell lines has been observed the remarkable level of expression.In conclusion, we confirmed the overexpression of YAP cell line in oral squamous cell carcinoma, it will be a great help to the study carried out in the future. Once you understand the mechanism of oncoprotien YAP in oral cancer cells, it seems possible to research and development of targeted tumor therapy agents in oral cancer."