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Oral squamous papilloma (OSP) is a common benign lesion of the oral mucosa that is induced by the human papillomavirus. To investigate the clinicopathological characteristics of OSP, we selected 135 patients diagnosed at the Seoul National University Dental Hospital. OSPs occurring in Koreans had a slight female predilection, with the male to female ratio being 1:1.6. The age ranged from 4 to 80 years old (average age: 47 years). The most frequent location was the soft palate (43.7%), followed by the tongue and gingiva. 11.1% of all patients presented with pain. There have been no reported cases of recurrence. On microscopic examination, two‐thirds of the lesions were parakeratinized, with almost all cases (99%) containing the koilocytes. In conclusion, there were no significant differences between the clinicopathological features of OSP in Korean and findings from previous studies. 
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