Disease

Oncocytoma

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0건 조회 6,170회 작성일 03-02-13 14:56

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Definition

  oncocyte로 구성된 양성의 salivary gland tumor

Clinical Features           

  ① older adults, eighth decade of life
  ② major salivary gland-특히 parotid gland
  ③ firm, slowly growing, painless mass

Histopathologis Features

  ① well - circumscribed tumor
  ② oncocyte – 풍부한 granular, eosinophilic cytoplasm가진sheets of large, polyhedral cells  
  ③ centrally located nuclei를 가짐
  ④ little stroma,  thin fibrovascular septa
  ⑤ granularity of the cells - overabundance of mitochondria
  ⑥ phosphotungstic acid - hematoxylin (PTAH) stain
  ⑦ glycogen - perodic acid - Schiff (PAS)  

Treatment &Prognosis

  ①surgical excision